Panel extins ac. antigene nucleare (ANA)
Panelul determină anticorpii îndreptați împotriva următoarelor antigene: Jo-1 (Hystidyl tRNA synthetase), PL-7 (Threonyl tRNA synthetase), PL-12 (Alanyl tRNA synthetase), EJ (Glycyl tRNA synthetase), OJ (Isoleucyl tRNA synthetase), KS (Asparaginyl tRNA synthetase), YARS (Tyrosyl tRNA synthetase (HA)), ZoA (Phenylalanyl tRNA synthetase), ZoB (Phenylalanyl tRNA synthetase), HMGCR (3-hydroxy-3methylglutaryl-coenzyme A reductase), SAE-1 (Small ubiquitin-like modifier activating enzyme), SAE-2 (Small ubiquitin-like modifier activating enzyme), SRP54 (Signal recognition particle), Mi-2 (Helicase protein-nuclear transcription), TIF1γ (Transcription Intermediary Factor 1), MDA5 (Melanoma differentiation associated protein 5 (CADM-140)), NXP2 (Nuclear matrix protein 2 (p140, MJ)), PMScl 100 (Human exosome complex), PMScl 75 (Human exosome complex), Scl-70 (DNA-topoisomerase I), centromer A (CENP A), centromer B (CENP B), RNA polymerase III (POLR3A), NOR90 (Nucleolar transcription factor 1 (Ubtf1)), Th/To (Ribonuclease P protein subunit 25 (Rpp25)), PDGFR-β (Platelet-derived growth factor receptor beta), U3 RNP - fibrillarin, Ro52 (TRIM21), Ro60 (Sjögren's-syndrome-related antigen A (SS-A)), La (Sjögren's-syndrome-related antigen B (SS-B)), RNP A (U1 small nuclear ribonucleoprotein A), RNP 68/70 (U1 small nuclear ribonucleoprotein 68/70 kDa), RNP C (U1 small nuclear ribonucleoprotein C), SmB (Smith antigen B), SmD (Smith antigen D), PCNA (Proliferating cell nuclear antigen), P0 (Ribosomal protein P0), Ku (p70/p80), nucleolin, histone, nucleozom, ADN dublu catenar (dsDNA), mitocondrii M2 (AMA-M2), DFS70 ( Dense fine speckled 70 antigen).
Metode și materiale folosite
- MetodaImunoblot
- Material uzualser (dop galben/roșu)
- Transport (temp. °C)2 - 8
- Stabilitatea probei7 zile la 2-8 °C
- Cantitate minimă1 ml
- Frecvența3/săptămână